Monitoring the stannous tin (Sn(II)) content in technetium-99m (99mTc) radiopharmaceuticals is essential for quality control. Differential pulse polarography is a straightforward, interference-free, and sensitive technique for this analysis mentioned by the IAEA (International Atomic Energy Agency) Technical Report Series No 466 as analysis method. Metrohm Application Note AN-V-219 describes the analysis for a cold kit for the preparation of sodium pertechnetate (99mTc) injection.
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