Front-and-centre in H3D’s diversification effort is the M400 Series, a compact and customizable module capable of high-resolution gamma spectroscopy in a range of medical imaging applications. “The M400 is an off-the-shelf commercial product that can be easily ‘tiled’ to form imaging arrays with enhanced sensitivity,” says Kaye, founder and CEO of H3D. “We anticipate broad applicability across multiple imaging modalities and clinical use cases. Specifically, the M Series forms the basis of a high-energy, high-flux spectrometer that’s able to image high-energy gamma rays produced during proton therapy (the spectrometer being tiled up with 16 M400 units – i.e. 64 CZT crystals and a total crystal volume of 310 cm3). Although this is still early-stage evaluation work, the long-term objective is an on-board imaging system to ensure that the bulk of the radiation payload from the proton treatment beam is deposited into the tumour rather than adjacent healthy tissue. The prompt gamma-ray emissions from proton interactions with tissue can be used to monitor the proton beam in vivo, providing real-time knowledge of tumour location, beam position, and beam penetration depth during treatment,” explains Hao Yang, a product development engineer at H3D.
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